Several drugs with this pharmacologic effect have caused decreased survival compared to placebo in patients with class III-IV heart failure [see Contraindications ] PLETAL (cilostazol) is a quinolinone derivative that inhibits cellular phosphodiesterase (more specific for phosphodiesterase III). Pletal is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). Patients may respond as early as 2 to 4 weeks after the initiation of therapy, but treatment for up to 12 weeks may be needed before a beneficial effect is experienced. Fexinidazole will increase the level or effect of cilostazol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Manufacturer Otsuka America Pharmaceutical, Inc. pletal drug class Decrease cilostazol dose by 50%; 3,4-dehydrocilostazol, an active metabolite, increased by 69% as a result of omeprazole inhibition of CYP2C19. It is used to reduce leg pain caused by poor circulation (intermittent claudication) Pletal is a prescription medication used to reduce the symptoms of intermittent claudication (pain in the legs when walking due to narrowing of blood vessels). It is used to reduce leg pain caused by poor circulation (intermittent claudication) Drug classes: Miscellaneous cardiovascular agents, Platelet aggregation inhibitors Medically reviewed by Drugs. Cilostazol improves the flow of blood through the blood vessels. Partners, Adage Capital Management, Arix Bioscience, pletal drug class BioMed Ventures, Lundbeckfonden Ventures, New Enterprise Associates, Pappas Capital, RiverVest Venture Partners and Sofinnova Investments. Cilostazol and several of its metabolites are inhibitors of phosphodiesterase III. Pharmacologic Class: Phosphodiesterase Inhibitor. This medicine also improves circulation by keeping platelets in the blood from sticking together and clotting. The recommended dosage of PLETAL is 100 mg twice daily taken at least half an hour before or two hours after breakfast and dinner. We routinely post information that may be serious, may become apparent with more widespread use of the report Pletal tab pletal 100 mg with VISA 120 the amount of packaging price 102 USD. Recommended dosage The recommended dosage of PLETAL is 100 mg twice daily taken at least half an hour before or two hours after breakfast and dinner Decrease cilostazol dose by 50%; 3,4-dehydrocilostazol, an active metabolite, increased by 69% as a result of omeprazole inhibition of CYP2C19. Cilostazol is 6- [4- (1-cyclohexyl-1 H -tetrazol-5-yl)butoxy]-3,4-dihydro-2 (1 H )-quinolinone, CAS-73963-72-1 Pletal; Available Dosage Forms: Tablet; Therapeutic Class: Platelet Aggregation Inhibitor. This medication may be prescribed for other uses. Pletal; Available Dosage Forms: Tablet; Therapeutic Class: Platelet Aggregation Inhibitor. Ask your doctor or pharmacist for more information. Find top topics, trends and opinion of pletal drug class you need on echemi. This medicine dilates arteries that supply blood to your legs. Avoid or Use Alternate Drug Check the news of pletal drug class. Combining pletal with other drugs that interfere with the blood clotting process may increase the likelihood of bleeding Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions, Lovastatin). Pletal is used to treat the symptoms of intermittent claudication Pletal is contraindicated in patients with heart failure of any severity. Therefore, a dose of 50 mg twice daily should be considered when drugs that may increase the concentration of cilostazol also are being used. The empirical formula of cilostazol is C 20 H 27 N 5 O 2, and its molecular weight is 369. Avoid or Use Alternate Drug Higher concentrations of cilostazol could increase the possibility of toxic effects.
